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Article

Evolutionary origins and diversification of testis-specific short histone H2A variants in mammals.

Genome research - 1 Apr 2018

Molaro Antoine, Young Janet M, Malik Harmit S

Abstract excerpt

Eukaryotic genomes must accomplish both compact packaging for genome stability and inheritance, as well as accessibility for gene expression. They do so using post-translational modifications of four ancient canonical histone proteins (H2A, H2B, H3, and H4) and by deploying histone variants with specialized chromatin functions. Some histone variants are conserved across all eukaryotes, whereas others are...

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Identifiers

PMID: 29549088
DOI: 10.1101/gr.229799.117
PMCID: PMC5880237

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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