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Biogenesis of mature piRNAs in <i>Caenorhabditis elegans</i> is dependent on orchestration between multiple ribonucleases and PRG-1

2021-12-29

Abstract excerpt

Piwi-interacting RNAs (piRNAs) are an animal-specific class of germline-enriched small non-coding RNAs that shape transcriptome, as well as ensure genomic integrity and fertility by regulating transposons and other selfish genetic elements. In Caenorhabditis elegans mature piRNAs are 21-nucleotides long, begin with a monophosphorylated uridine, and they associate with PRG-1 to form piRISCs that scan the transcrip...

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Literature Corpus work
107f6fd9-9806-57ef-895b-c4a718b0a8e9
DOI
10.1101/2021.12.29.474424
Open publication

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Biogenesis of mature piRNAs in <i>Caenorhabditis elegans</i> is dependent on orchestration between multiple ribonucleases and PRG-1DOI 10.1101/2021.12.29.474424
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