Article

The RNA phosphatase PIR-1 regulates endogenous small RNA pathways in <i>C. elegans</i>

2020-08-04

Abstract excerpt

<h4>SUMMARY</h4> Eukaryotic cells regulate 5’ triphosphorylated (ppp-) RNAs to promote cellular functions and prevent recognition by antiviral RNA sensors. For example, RNA capping enzymes possess triphosphatase domains that remove the γ phosphates of ppp-RNAs during RNA capping. Members of the closely related PIR1 family of RNA polyphosphatases remove both the β and γ phosphates from ppp-RNAs. Here we show that...

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Literature Corpus work: 380031dd-5eb4-5f02-b2f5-e0a05ceb65c2
DOI: 10.1101/2020.08.03.235143

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