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Article

piRNAs--the ancient hunters of genome invaders.

Genes & development - 15 Jul 2007

Hartig Julia Verena, Tomari Yukihide, Förstemann Klaus

Abstract excerpt

In addition to miRNAs and siRNAs, a third small RNA silencing system has been uncovered that prevents the spreading of selfish genetic elements. Production of the Piwi-associated RNAs (piRNAs), which mediate the silencing activity in this pathway, is initiated at a few master control regions within the genome. The nature of the primary piRNA-generating transcript is still unknown, but RNA interference (RNAi)-like...

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PMID: 17639076
DOI: 10.1101/gad.1567007

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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