Article
PID-1 is a novel factor that operates during 21U-RNA biogenesis in Caenorhabditis elegans.
Genes & development - 1 Apr 2014
de Albuquerque Bruno F M, Luteijn Maartje J, Cordeiro Rodrigues Ricardo J, van Bergeijk Petra, Waaijers Selma, Kaaij Lucas J T, Klein Holger, Boxem Mike, Ketting René F
Abstract excerpt
The Piwi-piRNA pathway represents a small RNA-based mechanism responsible for the recognition and silencing of invading DNA. Biogenesis of piRNAs (21U-RNAs) is poorly understood. In Caenorhabditis elegans, the piRNA-binding Argonaute protein PRG-1 is the only known player acting downstream from p...
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