Article

piRNA processing by a trimeric Schlafen-domain nuclease

2023-01-20

Abstract excerpt

Transposable elements are genomic parasites that expand within and spread between genomes 1 . Piwi proteins control transposon activity, notably in the germline 2,3 . These proteins recognize their targets through small RNA co-factors named piRNAs, making piRNA biogenesis a key specificity-determining step in this crucial genome immunity system. While the processing of piRNA precursors is an essential step in th...

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Literature Corpus work: 3e6c8b7d-df2e-580b-97e3-e1da48c15b0e
DOI: 10.1101/2023.01.19.524756

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