Article

Lipoprotein Signatures of Cholesteryl Ester Transfer Protein and HMG-CoA Reductase Inhibition

2018-04-05

Abstract excerpt

<h4>Background</h4> CETP inhibition reduces vascular event rates but confusion surrounds its low-density lipoprotein (LDL)-cholesterol effects. We sought to clarify associations of genetic inhibition of CETP on detailed lipoproteins. <h4>Methods and Results</h4> We used variants associated with CETP (rs247617) and HMGCR (rs12916) expression in 62,400 Europeans with detailed lipoprotein profiling from nuclear m...

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Literature Corpus work: 1040f276-cdf5-5418-b24e-4d0153a5fda9
DOI: 10.1101/295394

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