Back to search

Article

Comparing the effect profile of CETP in individuals of East Asian and European ancestries

2023-06-04

Abstract excerpt

<h4>Background</h4> Cholesteryl ester transfer protein (CETP) is a lipid drug target under development for coronary heart disease (CHD) in both European and East Asian populations. Previous drug target Mendelian randomization (MR) studies conducted in East Asians failed to show a CHD effect, which has been interpreted as lack of effectiveness of CETP inhibition for CHD prevention in this population. <h4>Objectives...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
0c2d8107-4704-55d0-9059-b438c5d2333f
DOI
10.1101/2023.05.26.23290616
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Comparing the effect profile of CETP in individuals of East Asian and European ancestriesDOI 10.1101/2023.05.26.23290616
Comparing the effect profile of cholesteryl ester transfer protein (CETP) in individuals of East Asian and European ancestriesSemantic proximity
Comparing the effects of CETP in East Asian and European ancestries: a Mendelian randomization study.Semantic proximity
Prioritizing protein targets for dyslipidaemia and cardiovascular diseases using Mendelian randomization in South AsiansSemantic proximity
Lipids, Blood Pressure, and Diabetes Mellitus on Risk of Cardiovascular Diseases in East Asians: A Mendelian Randomization StudySemantic proximity
Cholesteryl Ester Transfer Protein as a Drug Target for Cardiovascular DiseaseSemantic proximity
Cholesteryl ester transfer protein (CETP) as a drug target for cardiovascular diseaseSemantic proximity
Cholesteryl Ester Transfer Protein as a Drug Target for Cardiovascular DiseaseSemantic proximity
Lipoprotein signatures of cholesteryl ester transfer protein and HMG-CoA reductase inhibition.Semantic proximity
Lipoprotein Signatures of Cholesteryl Ester Transfer Protein and HMG-CoA Reductase InhibitionSemantic proximity
Validation of lipid-related therapeutic targets for coronary heart disease prevention using human geneticsSemantic proximity
Phenome-wide Mendelian randomization study of plasma triglyceride levels and 2600 disease traits.Semantic proximity
Validation of lipid-related therapeutic targets for coronary heart disease prevention using human geneticsSemantic proximity
Select a neighboring publication to make it the new centre.