Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

HDL Cholesterol Metabolism and the Risk of CHD: New Insights from Human Genetics.

Current cardiology reports - 4 Nov 2017

Vitali Cecilia, Khetarpal Sumeet A, Rader Daniel J

Abstract excerpt

PURPOSE OF REVIEW: Elevated high-density lipoprotein cholesterol levels in the blood (HDL-C) represent one of the strongest epidemiological surrogates for protection against coronary heart disease (CHD), but recent human genetic and pharmacological intervention studies have raised controversy about the causality of this relationship. Here, we review recent discoveries from human genome studies using new analytic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biomarkers
Share to Cholesterol, HDL
Share to Coronary Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Exome Sequencing

Share to Genome-Wide Association Study

Share to Lipid Metabolism

Share to Mendelian Randomization Analysis

Share to Molecular Targeted Therapy

Source

Identifiers

PMID: 29103089
DOI: 10.1007/s11886-017-0940-0

Genes

CETP
GALNT2
KLF14
LCAT
LIPG
SCARB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

HDL Cholesterol Metabolism and the Risk of CHD: New Insights from Human Genetics.PMID 29103089Read ↗

Human genetics of HDL: Insight into particle metabolism and functionSemantic proximity Read ↗

Genetic causes of high and low serum HDL-cholesterol.Semantic proximity Read ↗

HDL and atherosclerotic cardiovascular disease: genetic insights into complex biology.Semantic proximity Read ↗

Genetic-epidemiological evidence on genes associated with HDL cholesterol levels: a systematic in-depth review.Semantic proximity Read ↗

Genetics of HDL-C: a causal link to atherosclerosis?Semantic proximity Read ↗

Common genetic variation in multiple metabolic pathways influences susceptibility to low HDL-cholesterol and coronary heart disease.Semantic proximity Read ↗

Genetic determinants of HDL metabolism.Semantic proximity Read ↗

Beyond the genetics of HDL: why is HDL cholesterol inversely related to cardiovascular disease?Semantic proximity Read ↗

Mendelian disorders of high-density lipoprotein metabolism.Semantic proximity Read ↗

The value of HDL genetics.Semantic proximity Read ↗

HDL as a Causal Factor in Atherosclerosis: Insights from Human Genetics.Semantic proximity Read ↗

Identification of four novel genes contributing to familial elevated plasma HDL cholesterol in humans.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.