Article
Association of CETP Gene Variants With Risk for Vascular and Nonvascular Diseases Among Chinese Adults.
JAMA cardiology - 1 Jan 2018
Millwood Iona Y, Bennett Derrick A, Holmes Michael V, Boxall Ruth, Guo Yu, Bian Zheng, Yang Ling, Sansome Sam, Chen Yiping, Du Huaidong, Yu Canqing, Hacker Alex, Reilly Dermot F, Tan Yunlong, Hill Michael R, Chen Junshi, Peto Richard, Shen Hongbing, Collins Rory, Clarke Robert, Li Liming, Walters Robin G, Chen Zhengming
Abstract excerpt
Importance: Increasing levels of high-density lipoprotein (HDL) cholesterol through pharmacologic inhibition of cholesteryl ester transfer protein (CETP) is a potentially important strategy for prevention and treatment of cardiovascular disease (CVD). Objective: To use genetic variants in the CETP gene to assess potential risks and benefits of lifelong lower CETP activity on CVD and other outcomes. Design,...
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