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HDL cholesterol concentrations and risk of atherosclerotic cardiovascular disease - Insights from randomized clinical trials and human genetics.

Biochimica et biophysica acta. Molecular and cell biology of lipids - 1 Jan 2022

Kjeldsen Emilie Westerlin, Thomassen Jesper Qvist, Frikke-Schmidt Ruth

Abstract excerpt

Through seven decades the inverse association between HDL cholesterol concentrations and risk of atherosclerotic cardiovascular disease (ASCVD) has been observed in case-control and prospective cohort studies. This robust inverse association fuelled the enthusiasm towards development of HDL cholesterol increasing drugs, exemplified by the cholesteryl ester transfer protein (CETP) inhibitor trials and the...

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Identifiers

PMID: 34637926
DOI: 10.1016/j.bbalip.2021.159063

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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