Article
CETP (Cholesteryl Ester Transfer Protein) Concentration: A Genome-Wide Association Study Followed by Mendelian Randomization on Coronary Artery Disease.
Circulation. Genomic and precision medicine - 1 May 2018
Blauw Lisanne L, Li-Gao Ruifang, Noordam Raymond, de Mutsert Renée, Trompet Stella, Berbée Jimmy F P, Wang Yanan, van Klinken Jan B, Christen Tim, van Heemst Diana, Mook-Kanamori Dennis O, Rosendaal Frits R, Jukema J Wouter, Rensen Patrick C N, Willems van Dijk Ko
Abstract excerpt
BACKGROUND: We aimed to identify independent genetic determinants of circulating CETP (cholesteryl ester transfer protein) to assess causal effects of variation in CETP concentration on circulating lipid concentrations and cardiovascular disease risk. METHODS: A genome-wide association discovery and replication study on serum CETP concentration were embedded in the NEO study (Netherlands Epidemiology of Obesity)....
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