Article

Are Genetic Interactions Influencing Gene Expression Evidence for Biological Epistasis or Statistical Artifacts?

2015-06-05

Abstract excerpt

The importance of epistasis – or statistical interactions between genetic variants – to the development of complex disease in humans has long been controversial. Genome-wide association studies of statistical interactions influencing human traits have recently become computationally feasible and have identified many putative interactions. However, several factors that are difficult to address confound the statisti...

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Literature Corpus work: 0fdadeb9-5dd3-5e84-a386-978fe42b3e66
DOI: 10.1101/020479

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