Article
Layers of epistasis: genome-wide regulatory networks and network approaches to genome-wide association studies.
Wiley interdisciplinary reviews. Systems biology and medicine - 1 Jan 2000
Cowper-Sal lari Richard, Cole Michael D, Karagas Margaret R, Lupien Mathieu, Moore Jason H
Abstract excerpt
The conceptual foundation of the genome-wide association study (GWAS) has advanced unchecked since its conception. A revision might seem premature as the potential of GWAS has not been fully realized. Multiple technical and practical limitations need to be overcome before GWAS can be fairly criti...
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