Article

Hypothesis-free identification of modulators of genetic risk factors

2015-11-30

Abstract excerpt

Genetic risk factors often localize in non-coding regions of the genome with unknown effects on disease etiology. Expression quantitative trait loci (eQTLs) help to explain the regulatory mechanisms underlying the association of genetic risk factors with disease. More mechanistic insights can be derived from knowledge of the context, such as cell type or the activity of signaling pathways, influencing the nature a...

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Literature Corpus work: f67aa93a-9618-5065-a908-6a5996b67c77
DOI: 10.1101/033217

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