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Article

Modifier effects between regulatory and protein-coding variation.

PLoS genetics - 1 Oct 2008

Dimas Antigone S, Stranger Barbara E, Beazley Claude, Finn Robert D, Ingle Catherine E, Forrest Matthew S, Ritchie Matthew E, Deloukas Panos, Tavaré Simon, Dermitzakis Emmanouil T

Abstract excerpt

Genome-wide associations have shown a lot of promise in dissecting the genetics of complex traits in humans with single variants, yet a large fraction of the genetic effects is still unaccounted for. Analyzing genetic interactions between variants (epistasis) is one of the potential ways forward....

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Share to Amino Acid Substitution
Share to Analysis of Variance
Share to Epistasis, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Linkage Disequilibrium

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Share to Regulatory Sequences, Nucleic Acid

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Source

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Identifiers

PMID: 18974877
DOI: 10.1371/journal.pgen.1000244
PMCID: PMC2570624

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18974877-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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