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HiCRes: a computational method to estimate and predict the resolution of HiC libraries

2020-09-22

Abstract excerpt

Three-dimensional (3D) conformation of the chromatin is crucial to stringently regulate gene expression patterns and DNA replication in a cell-type specific manner. HiC is a key technique for measuring 3D chromatin interactions genome wide. Estimating and predicting the resolution of a library is an essential step in any HiC experimental design. Here, we present the mathematical concepts to estimate the resolution...

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Identifiers and source

Literature Corpus work
0f5b0981-68f2-5b15-beaf-d9fe6edb8972
DOI
10.1101/2020.09.22.307967
Open publication

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HiCRes: a computational method to estimate and predict the resolution of HiC librariesDOI 10.1101/2020.09.22.307967
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