Article

Measuring the reproducibility and quality of Hi-C data

2017-09-14

Abstract excerpt

Hi-C is currently the most widely used assay to investigate the 3D organization of the genome and to study its role in gene regulation, DNA replication, and disease. However, Hi-C experiments are costly to perform and involve multiple complex experimental steps; thus, accurate methods for measuring the quality and reproducibility of Hi-C data are essential to determine whether the output should be used further in...

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Literature Corpus work: c66708b1-c3a2-5e39-81e4-a89f570ea082
DOI: 10.1101/188755

Open publication

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