Article

GAMIBHEAR: whole-genome haplotype reconstruction from Genome Architecture Mapping data

2020-01-31

Abstract excerpt

<h4>Motivation</h4> Genome Architecture Mapping (GAM) was recently introduced as a digestion- and ligation-free method to detect chromatin conformation. Orthogonal to existing approaches based on chromatin conformation capture (3C), GAM’s ability to capture both inter- and intra-chromosomal contacts from low amounts of input data makes it particularly well suited for allele-specific analyses in a clinical setting...

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Literature Corpus work: 0f41aa8f-d946-548f-b1d8-a82d5e5f68c0
DOI: 10.1101/2020.01.30.927061

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