Back to search

Article

Extended haplotype phasing of <i>de novo</i> genome assemblies with FALCON-Phase

2018-05-21

Abstract excerpt

<h4>ABSTRACT</h4> Haplotype-resolved genome assemblies are important for understanding how combinations of variants impact phenotypes. These assemblies can be created in various ways, such as use of tissues that contain single-haplotype (haploid) genomes, or by co-sequencing of parental genomes, but these approaches can be impractical in many situations. We present FALCON-Phase, which integrates long-read sequenc...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
563a73e4-4f7a-59b4-813f-cd1e01843c75
DOI
10.1101/327064
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Extended haplotype phasing of <i>de novo</i> genome assemblies with FALCON-PhaseDOI 10.1101/327064
Extended haplotype-phasing of long-read de novo genome assemblies using Hi-C.Semantic proximity
Accurate chromosome-scale haplotype-resolved assembly of human genomesSemantic proximity
Chromosome-scale, haplotype-resolved assembly of human genomes.Semantic proximity
How well can we create phased, diploid, human genomes?: An assessment of FALCON-Unzip phasing using a human trioSemantic proximity
Determinants of haplotype phasing accuracy in long-read human genome sequencingSemantic proximity
Extending partial haplotypes to full genome haplotypes using chromosome conformation capture data.Semantic proximity
Phasing Diploid Genome Assembly Graphs with Single-Cell Strand SequencingSemantic proximity
Gaps and complex structurally variant loci in phased genome assembliesSemantic proximity
A fully phased accurate assembly of an individual human genomeSemantic proximity
Efficient and accurate near telomere-to-telomere haplotype reconstruction of diploid genomesSemantic proximity
TinkerHap - A Novel Read-Based Phasing Algorithm with Integrated Multi-Method Support for Enhanced AccuracySemantic proximity
TinkerHap - A Novel Read-Based Phasing Algorithm with Integrated Multi-Method Support for Enhanced AccuracySemantic proximity
Select a neighboring publication to make it the new centre.