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Article

MethHaplo: combining allele-specific DNA methylation and SNPs for haplotype region identification.

BMC bioinformatics - 12 Oct 2020

Zhou Qiangwei, Wang Ze, Li Jing, Sung Wing-Kin, Li Guoliang

Abstract excerpt

BACKGROUND: DNA methylation is an important epigenetic modification that plays a critical role in most eukaryotic organisms. Parental alleles in haploid genomes may exhibit different methylation patterns, which can lead to different phenotypes and even different therapeutic and drug responses to diseases. However, to our knowledge, no software is available for the identification of DNA methylation haplotype...

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Share to Alleles
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Share to Epigenesis, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymorphism, Single Nucleotide

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Identifiers

PMID: 33045983
DOI: 10.1186/s12859-020-03798-7
PMCID: PMC7552496

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