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SurpHer: a genetically encoded ratiometric sensor for dynamic extracellular pH imaging

2026-05-21

Abstract excerpt

Extracellular pH is a key microenvironmental factor shaping cell physiology and disease, creating a need for quantitative biosensors that can capture dynamic changes in pH e at the surface of individual living cells. Here, we develop a genetically encoded, ratiometric extracellular pH biosensor through systematic screening of a modular library of membrane-display designs that combine SEpHluorin with a pH-stable r...

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Literature Corpus work
0d5f12a3-0328-5621-866c-18cdb2f75388
DOI
10.64898/2026.05.18.725923
Open publication

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SurpHer: a genetically encoded ratiometric sensor for dynamic extracellular pH imagingDOI 10.64898/2026.05.18.725923
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