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Article

Engineering a riboswitch-based genetic platform for the self-directed evolution of acid-tolerant phenotypes.

Nature communications - 4 Sept 2017

Pham Hoang Long, Wong Adison, Chua Niying, Teo Wei Suong, Yew Wen Shan, Chang Matthew Wook

Abstract excerpt

Environmental pH is a fundamental signal continuously directing the metabolism and behavior of living cells. Programming the precise cellular response toward environmental pH is, therefore, crucial for engineering cells for increasingly sophisticated functions. Herein, we engineer a set of riboswitch-based pH-sensing genetic devices to enable the control of gene expression according to differential environmental...

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Identifiers

PMID: 28871084
DOI: 10.1038/s41467-017-00511-w
PMCID: PMC5583362

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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