Article

A ratiometric pH sensor for Gram-positive and Gram-negative bacteria

2025-09-09

Abstract excerpt

Fluctuating environments can lead to phenotypic heterogeneity within a monoclonal bacterial population, especially in response to antibiotics or the human immune system. Methods are required to analyze the physiology of single cells to understand how individual cells interact with their environment and adapt to pH stress. We report a ratiometric, fluorescent probe to sense cytoplasmic pH in bacteria. Our probes ar...

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Identifiers and source

Literature Corpus work: 1ec70a6d-3e3c-5aaa-b99d-e38399272f3b
DOI: 10.1101/2025.09.09.675137

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