Article

A rigorous benchmarking of alignment-based HLA typing algorithms for RNA-seq data

2023-05-24

Abstract excerpt

Accurate identification of human leukocyte antigen (HLA) alleles is essential for various clinical and research applications, such as transplant matching and drug sensitivities. Recent advances in RNA-seq technology have made it possible to impute HLA types from sequencing data, spurring the development of a large number of computational HLA typing tools. However, the relative performance of these tools is unknown...

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Identifiers and source

Literature Corpus work: 8d920086-af12-533f-99a6-413c17aba554
DOI: 10.1101/2023.05.22.541750

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