Article

Benchmark of tools for in silico prediction of MHC class I and class II genotypes from NGS data

2023-04-25

Abstract excerpt

<h4>Background: </h4> The Human Leukocyte Antigen (HLA) genes are a group of highly polymorphic genes that are located in the Major Histocompatibility Complex (MHC) region on chromosome 6. The HLA genotype affects the presentability of tumour antigens to the immune system. While knowledge of these genotypes is of utmost importance to study differences in immune responses between cancer patients, gold standard, PCR...

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Literature Corpus work: 6b3d2de3-5a66-572f-93bc-a66a93417933
DOI: 10.21203/rs.3.rs-2837161/v1

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