Article

Quantifying HLA transcripts by genotype in chimeric mixtures at single-cell resolution

2025-09-17

Abstract excerpt

<h4>ABSTRACT</h4> Gene products from the highly variable major histocompatibility locus, including HLA, are essential for self-recognition and immune surveillance of malignancy. Following allogeneic hematopoietic cell transplantation (alloHCT), genetic and epigenetic alterations in HLA can drive disease recurrence, making precise HLA assessment critical for determining future therapy. However, current methods lac...

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Literature Corpus work: 7613da91-4a73-55cd-beb0-d5e0733c7a50
DOI: 10.1101/2025.09.12.675951

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