Article

Transition from a meiotic to a somatic-like DNA damage response during the pachytene stage in mouse meiosis

2018-05-22

Abstract excerpt

Homologous recombination (HR) is the principal mechanism of DNA repair acting during meiosis and is fundamental for the segregation of chromosomes and the increase of genetic diversity. Nevertheless, non-homologous end joining (NHEJ) mechanisms also act during meiosis, mainly in response to exogenously-induced DNA damage in late stages of first meiotic prophase. In order to better understand the relationship betwe...

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Literature Corpus work: 0cf39bdf-86f7-5073-8504-43643e42f174
DOI: 10.1101/328278

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