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The BRCA1-BARD1 complex associates with the synaptonemal complex and pro-crossover factors and influences RAD-51 dynamics during <i>Caenorhabditis elegans</i> meiosis

2018-03-11

Abstract excerpt

During meiosis, the maternal and paternal homologous chromosomes must align along their entire length and recombine to achieve faithful segregation in the gametes. Meiotic recombination is accomplished through the formation of DNA double-strand breaks, a subset of which can mature into crossovers to link the parental homologous chromosomes and promote their segregation. Breast and ovarian cancer susceptibility pro...

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Literature Corpus work
5bfcfa95-e6ec-59bf-b9ee-7acb65d28f8e
DOI
10.1101/280214
Open publication

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The BRCA1-BARD1 complex associates with the synaptonemal complex and pro-crossover factors and influences RAD-51 dynamics during <i>Caenorhabditis elegans</i> meiosisDOI 10.1101/280214
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