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Article

The Mre11 complex influences DNA repair, synapsis, and crossing over in murine meiosis.

Current biology : CB - 20 Feb 2007

Cherry Sheila M, Adelman Carrie A, Theunissen Jan W, Hassold Terry J, Hunt Patricia A, Petrini John H J

Abstract excerpt

The Mre11 complex (consisting of MRE11, RAD50, and NBS1/Xrs2) is required for double-strand break (DSB) formation, processing, and checkpoint signaling during meiotic cell division in S. cerevisiae. Whereas studies of Mre11 complex mutants in S. pombe and A. thaliana indicate that the complex has other essential meiotic roles , relatively little is known regarding the functions of the complex downstream of...

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Share to Acid Anhydride Hydrolases
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 17291760
DOI: 10.1016/j.cub.2006.12.048
PMCID: PMC1839861

Genes

MLH1
MRE11
RAD50

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The Mre11 complex influences DNA repair, synapsis, and crossing over in murine meiosis.PMID 17291760Read ↗

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