Article

SINBAD: a flexible tool for single cell DNA methylation data

2021-10-24

Abstract excerpt

DNA methylation is an epigenetic mark that has vital importance in both development and disease. Single cell bisulfite sequencing technologies enable profiling of the methylome at high resolution, providing the basis for dissecting the heterogeneity and dynamics of DNA methylation in complex tissues and over time. Despite the rapid increase in the number of experimental protocols for methylome sequencing, analytic...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 04ab553a-5987-5411-9382-200ae05e13be
DOI: 10.1101/2021.10.23.465577

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

SINBAD: a flexible tool for single cell DNA methylation dataDOI 10.1101/2021.10.23.465577Read

scTAM-seq enables targeted high-confidence analysis of DNA methylation in single cellsSemantic proximity Read

MethylStar: A fast and robust pre-processing pipeline for bulk or single-cell whole-genome bisulfite sequencing dataSemantic proximity Read

NGSmethDB: an updated genome resource for high quality, single-cytosine resolution methylomes.Semantic proximity Read

ModSeqR: An R package for efficient analysis of modified nucleotide dataSemantic proximity Read

Single-cell DNA methylation analysis tool Amethyst reveals distinct noncanonical methylation patterns in human glial cellsSemantic proximity Read

Investigating the potential of single-cell DNA methylation data to detect allele-specific methylation and imprinting.Semantic proximity Read

DiffMethylTools: a toolbox of the detection, annotation and visualization of differential DNA methylationSemantic proximity Read

High-coverage allele-resolved single-cell DNA methylation profiling by scDEEP-mC reveals cell lineage, X-inactivation state, and replication dynamicsSemantic proximity Read

High-coverage allele-resolved single-cell DNA methylation profiling reveals cell lineage, X-inactivation state, and replication dynamics.Semantic proximity Read

wgbstools: A computational suite for DNA methylation sequencing data representation, visualization, and analysisSemantic proximity Read

Performance comparison and in-silico harmonisation of commercial platforms for DNA methylome analysis by targeted bisulfite sequencingSemantic proximity Read

Atlas-scale Single-cell DNA Methylation Profiling with sciMETv3Semantic proximity Read