Article

Transcription factor occupancy is affected by genetic variation in the white adipose tissue of C57BL6/j and 129S1/SvImJ mice

2025-05-13

Abstract excerpt

Most of the disease associated genetic variants identified in genome wide association studies have been mapped to the non-coding regions of the genome. One of the leading mechanisms by which these variants are thought to affect disease susceptibility is by altering transcription factor (TF) binding. Even though inbred mouse strains have been commonly used to investigate polygenic diseases, less is known on how the...

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Literature Corpus work: 0c572502-c1cb-582b-b741-57342bcd2804
DOI: 10.1101/2025.05.08.652810

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