Article

Chromatin variation associated with liver metabolism is mediated by transposable elements

2016-05-10

Abstract excerpt

<h4>Background</h4> Functional regulatory regions in eukaryotic genomes are characterized by the disruption of nucleosomes leading to accessible chromatin. The modulation of chromatin accessibility is one of the key mediators of transcriptional regulation and variation in chromatin accessibility across individuals has been liked to complex traits and disease susceptibility. While mechanisms responsible for chroma...

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Literature Corpus work: f7ea006a-088d-58d5-9bd1-5328daa5ecf0
DOI: 10.1101/052571

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