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Article

Allele-specific expression and eQTL analysis in mouse adipose tissue.

BMC genomics - 13 Jun 2014

Hasin-Brumshtein Yehudit, Hormozdiari Farhad, Martin Lisa, van Nas Atila, Eskin Eleazar, Lusis Aldons J, Drake Thomas A

Abstract excerpt

BACKGROUND: The simplest definition of cis-eQTLs versus trans, refers to genetic variants that affect expression in an allele specific manner, with implications on underlying mechanism. Yet, due to technical limitations of expression microarrays, the vast majority of eQTL studies performed in the last decade used a genomic distance based definition as a surrogate for cis, therefore exploring local rather than...

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Share to Adipose Tissue
Share to Alleles
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymorphism, Single Nucleotide

Share to Quantitative Trait Loci

Source

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Identifiers

PMID: 24927774
DOI: 10.1186/1471-2164-15-471
PMCID: PMC4089026

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