Article

Formal Statistical Replication Analysis in Lung Cancer Genome-Wide Association Studies

2025-10-03

Abstract excerpt

Dozens of genome-wide association studies (GWAS) have identified thousands of single nucleotide polymor-phisms (SNPs) associated with lung cancer risk. However, it remains challenging to translate these findings to clinical insights. One well-known obstacle is the large amount of type I error attached to GWAS; attempted solutions such as setting a p -value threshold across multiple cohorts or looking for small met...

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Literature Corpus work: 0c3cc47f-25ff-58dd-a2da-565856f6bf36
DOI: 10.1101/2025.10.02.25337130

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