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Article

Is replication the gold standard for validating genome-wide association findings?

PloS one - 1 Jan 2008

Liu Yong-Jun, Papasian Christopher J, Liu Jian-Feng, Hamilton James, Deng Hong-Wen

Abstract excerpt

With the advent of genome-wide association (GWA) studies, researchers are hoping that reliable genetic association of common human complex diseases/traits can be detected. Currently, there is an increasing enthusiasm about GWA and a number of GWA studies have been published. In the field a common practice is that replication should be used as the gold standard to validate an association finding. In this article,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 19112512
DOI: 10.1371/journal.pone.0004037
PMCID: PMC2605260

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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