Functional studies of lung cancer GWAS beyond association.

doi:10.1093/hmg/ddac140

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Article

Functional studies of lung cancer GWAS beyond association.

Human molecular genetics - 20 Oct 2022

Long Erping, Patel Harsh, Byun Jinyoung, Amos Christopher I, Choi Jiyeon

Abstract excerpt

Fourteen years after the first genome-wide association study (GWAS) of lung cancer was published, approximately 45 genomic loci have now been significantly associated with lung cancer risk. While functional characterization was performed for several of these loci, a comprehensive summary of the current molecular understanding of lung cancer risk has been lacking. Further, many novel computational and experimental...

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PMID: 35776125
DOI: 10.1093/hmg/ddac140
PMCID: PMC9585683

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