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Article

SNP characteristics predict replication success in association studies.

Human genetics - 1 Dec 2014

Gorlov Ivan P, Moore Jason H, Peng Bo, Jin Jennifer L, Gorlova Olga Y, Amos Christopher I

Abstract excerpt

Successful independent replication is the most direct approach for distinguishing real genotype-disease associations from false discoveries in genome-wide association studies (GWAS). Selecting SNPs for replication has been primarily based on P values from the discovery stage, although additional characteristics of SNPs may be used to improve replication success. We used disease-associated SNPs from more than...

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Identifiers

PMID: 25273843
DOI: 10.1007/s00439-014-1493-6
PMCID: PMC4384517

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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