Article

Could Metformin use reduce abdominal aortic aneurysm risk? A Mendelian randomisation study using known Metformin targets

2023-10-13

Abstract excerpt

<h4>Introduction</h4> An abdominal aortic aneurysm (AAA) is a swelling of the main artery in the body estimated to affect 0.92% of adults (aged 30-79) worldwide. Rupture is often fatal and surgical intervention may be offered if the risk of rupture is high. There is no treatment to prevent AAA or to slow aneurysm growth aside from dietary and lifestyle recommendations. Metformin, a drug prescribed to treat type 2...

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Literature Corpus work: 0b71f6fe-6a4b-50c4-87ed-37d4dda47d11
DOI: 10.1101/2023.10.13.23293381

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