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Deciphering the Role of Metformin in Abdominal Aortic Aneurysm Progression: Insights from Two-Step Mendelian Randomization and Colocalization Analysis

2025-06-27

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<title>Abstract</title> <p><bold>Objective: </bold>Our research sought to investigate the relationship between metformin and abdominal aortic aneurysm (AAA) risk. We aimed to contribute to the current understanding of metformin's potential as a pharmaceutical intervention for AAA and explore the genetic facets influencing its effect. <bold>Methods: </bold>The methods encompassed meta-analysis, Mendelian Randomiza...

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Literature Corpus work: db79fcc4-f07a-5020-83b4-79dfe0cfa65c
DOI: 10.21203/rs.3.rs-6834737/v1

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