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Article

Genetic Predisposition to Diabetes and Abdominal Aortic Aneurysm: A Two Stage Mendelian Randomisation Study.

European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery - 1 Mar 2022

Morris Dylan R, Jones Gregory T, Holmes Michael V, Bown Matthew J, Bulbulia Richard, Singh Tejas P, Golledge Jonathan

Abstract excerpt

OBJECTIVE: Observational studies demonstrate an inverse association between type II diabetes and abdominal aortic aneurysm (AAA) for reasons that are unclear. The aim of this study was to clarify the causal association between type II diabetes predisposition and AAA using Mendelian randomisation. METHODS: Effect estimates for single nucleotide polymorphisms (SNPs) associated with diabetes were obtained from the...

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Share to Aortic Aneurysm, Abdominal
Share to Aortic aneurysm repair treatments

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Diabetes Mellitus, Type 2

Share to Genetic Associations and Epidemiology

Share to Genetic Predisposition to Disease

Share to Genome-Wide Association Study

Share to Mendelian Randomization Analysis

Share to Polymorphism, Single Nucleotide

Source

Identifiers

PMID: 34916110
DOI: 10.1016/j.ejvs.2021.10.038

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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