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Article

Association between MTHFR C677T polymorphism and abdominal aortic aneurysm risk: A comprehensive meta-analysis with 10,123 participants involved.

Medicine - 1 Sept 2016

Liu Jie, Jia Xin, Li Haifeng, Jia Senhao, Zhang Minhong, Xu Yongle, Du Xin, Zhang Nianrong, Lu Weihang, Guo Wei

Abstract excerpt

BACKGROUND: Abdominal aortic aneurysm (AAA) is a life-threatening condition. A number of studies reported the association between methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism and AAA risk, but substantial controversial findings were observed and the strength of the association remains unclear. OBJECTIVE: The aim of this study was to investigate the aforementioned association in the overall...

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Identifiers

PMID: 27603386
DOI: 10.1097/MD.0000000000004793
PMCID: PMC5023909

Genes

MTHFR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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