Article

Lipoprotein (a) is associated with increased risk of Abdominal Aortic Aneurysm

2024-09-14

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Introduction</h4> Lipoprotein(a) (Lp(a)) is a circulating apolipoprotein B (ApoB) containing particle that has been observationally linked to atherosclerotic cardiovascular disease and is the target of emerging therapeutics. Recent work has highlighted the role of circulating lipoproteins in abdominal aortic aneurysm (AAA). We sought to triangulate human observational and genetic evidence to...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: a9e8fdbf-e24e-5aad-974c-e387488cf5c3
DOI: 10.1101/2024.09.13.24313646

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Lipoprotein (a) is associated with increased risk of Abdominal Aortic AneurysmDOI 10.1101/2024.09.13.24313646Read

A variant in LDLR is associated with abdominal aortic aneurysm.Semantic proximity Read

Differential Risk Profiles of Incident Abdominal Aortic Aneurysms in Specific Subgroups: A Large Cohort-based Study.Semantic proximity Read

Genetic Association of Lipids and Lipid Drug Targets With Abdominal Aortic Aneurysm: A Meta-analysis.Semantic proximity Read

Plasma proteomics reveals the potential causal impact of extracellular matrix proteins on abdominal aortic aneurysmSemantic proximity Read

Multi-ancestry GWAS deciphers genetic architecture of abdominal aortic aneurysm and highlights<i>PCSK9</i>as a therapeutic targetSemantic proximity Read

Associations of Genetically Predicted Lp(a) (Lipoprotein [a]) Levels With Cardiovascular Traits in Individuals of European and African Ancestry.Semantic proximity Read

Understanding the pathogenesis of abdominal aortic aneurysmsSemantic proximity Read

Genome-wide association meta-analysis identifies risk loci for abdominal aortic aneurysm and highlights PCSK9 as a therapeutic targetSemantic proximity Read

Pathophysiology of AAA: heredity vs environment.Semantic proximity Read

Genetic evidence for lifestyle and cardiometabolic factors on the risk of aortic aneurysms: A comprehensive Mendelian randomization study.Semantic proximity Read

Circulating inflammatory proteins and abdominal aortic aneurysm: A two-sample Mendelian randomization and colocalization analyses.Semantic proximity Read

Shared Genetic Susceptibility between Abdominal Aortic Aneurysm and Cardiometabolic TraitsSemantic proximity Read