Article

Pla2g12b is Essential for Expansion of Nascent Lipoprotein Particles

2022-08-03

Abstract excerpt

<h4>SUMMARY</h4> Triglyceride-rich lipoproteins (TRLs) are micelle-like particles that enable efficient transport of lipids throughout the bloodstream, but also promote atherosclerotic cardiovascular disease. Despite this central relevance to cardiovascular disease, very little is known about how lipids are loaded onto nascent TRLs prior to secretion. Here we show that Pla2g12b, a gene with no previously describe...

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Literature Corpus work: 09286260-4c0e-53f6-9df9-ce96651d2255
DOI: 10.1101/2022.08.02.502564

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