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Article

The GPIHBP1-LPL complex and its role in plasma triglyceride metabolism: Insights into chylomicronemia.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie - 31 Dec 2023

Jiang Shali, Ren Zhuoqun, Yang Yutao, Liu Qiming, Zhou Shenghua, Xiao Yichao

Abstract excerpt

GPIHBP1 is a protein found in the endothelial cells of capillaries that is anchored by glycosylphosphatidylinositol and binds to high-density lipoproteins. GPIHBP1 attaches to lipoprotein lipase (LPL), subsequently carrying the enzyme and anchoring it to the capillary lumen. Enabling lipid metabolism is essential for the marginalization of lipoproteins alongside capillaries. Studies underscore the significance of...

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PMID: 37951027
DOI: 10.1016/j.biopha.2023.115874

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The GPIHBP1-LPL complex and its role in plasma triglyceride metabolism: Insights into chylomicronemia.PMID 37951027Read ↗

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