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Multiparametric Platform for Profiling Lipid Trafficking in Human Leukocytes: Application for Hypercholesterolemia

2021-04-19

Abstract excerpt

<h4>Summary</h4> Systematic insight into cellular dysfunctions can improve understanding of disease etiology, risk assessment and patient stratification. We present a multiparametric high-content imaging platform enabling quantification of low-density lipoprotein (LDL) uptake and lipid storage in cytoplasmic droplets of primary leukocyte subpopulations. We validated this platform with samples from 65 individuals...

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Literature Corpus work
e0ceafc1-09d9-5042-a8da-7847df8fc5bd
DOI
10.1101/2021.04.19.440471
Open publication

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Multiparametric Platform for Profiling Lipid Trafficking in Human Leukocytes: Application for HypercholesterolemiaDOI 10.1101/2021.04.19.440471
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