Article

Loss of <i>asgr1a</i> leads to the secretion of excess dietary cholesterol in zebrafish

2024-06-29

Abstract excerpt

One of the major pathways to clear glycoproteins from circulation is via the liver-specific asialoglycoprotein receptor (ASGPR). Loss of asialoglycoprotein receptor 1 ( ASGR1 ), the major subunit of ASGPR, was recently found to correlate with lower levels of plasma apolipoprotein B- containing lipoproteins (B-lps) and a profoundly reduced risk of cardiovascular disease in humans. We set out to identify the zebraf...

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Literature Corpus work: 1947c7ce-25c6-5f48-ad3d-f941acd0a4be
DOI: 10.1101/2024.06.26.600848

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Loss of <i>asgr1a</i> leads to the secretion of excess dietary cholesterol in zebrafishDOI 10.1101/2024.06.26.600848Read

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