Article

Integrating genomic, transcriptomic and epigenetic data to identify phenotypically impactful driver pathways in glioblastoma

2025-03-06

Abstract excerpt

Glioblastoma multiforme (GBM), a highly aggressive brain tumor characterized by molecular hetero-geneity, necessitates integrative approaches to decipher driver pathways and therapeutic vulnerabilities. Here, we present gtePIDP , a computational framework that systematically integrates multi-omics data (genomic, transcriptomic, epigenetic) to identify Phenotypically Impactful Driver Pathways through dual evaluati...

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Literature Corpus work: ab91842f-d562-5c95-bd09-afd6ecae5f8d
DOI: 10.1101/2025.02.28.640792

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