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Article

A shift from kinesin 5-dependent metaphase spindle function during preimplantation development in mouse

22 May 2009

Abstract excerpt

Microtubules within meiotic and mitotic spindles continually move towards spindle poles in a process termed poleward flux, which is essential for spindle integrity and faithful chromosome segregation. Kinesin 5 is a longstanding candidate for a molecular motor that might drive poleward flux, and has been shown to drive flux and to be necessary for spindle bipolarity in Xenopus egg extracts. However, kinesin 5 is...

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PMID: 19465601
DOI: 10.1242/dev.035089

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A shift from kinesin 5-dependent metaphase spindle function during preimplantation development in mousePMID 19465601Read ↗

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