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Article

Novel potential mitotic motor protein encoded by the fission yeast cut7+ gene.

Nature - 11 Oct 1990

Hagan I, Yanagida M

Abstract excerpt

The structure equivalent to higher eukaryotic centrosomes in fission yeast, the nuclear membrane-bound spindle pole body, is inactive during interphase. On transition from G2 to M phase of the cell cycle, the spindle pole body duplicates; the daughter pole bodies seed microtubules which interdigitate to form a short spindle that elongates to span the nucleus at metaphase. We have identified two loci which, when...

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Identifiers

PMID: 2145514
DOI: 10.1038/347563a0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

Novel potential mitotic motor protein encoded by the fission yeast cut7+ gene.PMID 2145514Read ↗

Kinesin-related cut7 protein associates with mitotic and meiotic spindles in fission yeast.Semantic proximity Read ↗

Mutations in the bimC box of Cut7 indicate divergence of regulation within the bimC family of kinesin related proteins.Semantic proximity Read ↗

Kinesin-5/Cut7 moves bidirectionally on fission-yeast spindles with activity that increases in anaphaseSemantic proximity Read ↗

The fission yeast cut1+ gene regulates spindle pole body duplication and has homology to the budding yeast ESP1 gene.Semantic proximity Read ↗

Distinct regions of the kinesin-5 C-terminal tail are essential for mitotic spindle midzone localization and sliding force.Semantic proximity Read ↗

cut11(+): A gene required for cell cycle-dependent spindle pole body anchoring in the nuclear envelope and bipolar spindle formation in Schizosaccharomyces pombe.Semantic proximity Read ↗

Kinesin-14 and kinesin-5 antagonistically regulate microtubule nucleation by γ-TuRC in yeast and human cells.Semantic proximity Read ↗

pkl1(+)and klp2(+): Two kinesins of the Kar3 subfamily in fission yeast perform different functions in both mitosis and meiosis.Semantic proximity Read ↗

Bypassing anaphase by fission yeast cut9 mutation: requirement of cut9+ to initiate anaphase.Semantic proximity Read ↗

The bimB3 mutation of Aspergillus nidulans uncouples DNA replication from the completion of mitosis.Semantic proximity Read ↗

Fission yeast cut3 and cut14, members of a ubiquitous protein family, are required for chromosome condensation and segregation in mitosis.Semantic proximity Read ↗

The fission yeast SPB component Cut12 links bipolar spindle formation to mitotic control.Semantic proximity Read ↗

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